Medizinische Fakultät

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Die sichtbarsten Arbeiten der Medizinischen Fakultät 2018, JIF > 20

Längin M1, Mayr T1, Reichart B2, Michel S2, Buchholz S2, Guethoff S2, Dashkevich A2, Baehr A, Egerer S, ..., Abicht JM1
Consistent success in life-supporting porcine cardiac xenotransplantation.
Nature 2018; 564: 430-433 (JIF2017 41,6)
1 Klinik für Anästhesiologie
2 Herzchirurgische Klinik und Poliklinik

Hofweber M1, Hutten S1, Bourgeois B, Spreitzer E, Niedner-Boblenz A, Schifferer M, Ruepp MD, Simons M, Niessing D, ..., Dormann D1
Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation.
Cell 2018; 173: 706-719.e13 (JIF2017 31,4)
1 Biomedizinisches Zentrum, Lehrstuhl für Zellbiologie

Malik R1, Chauhan G, Traylor M, Sargurupremraj M, Okada Y, Mishra A, Rutten-Jacobs L, Giese AK, van der Laan SW,…, Dichgans M1,
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.
Nat Genet 2018; 50: 524-537 (JIF2017 27,1)
1 Institut für Schlaganfall- und Demenzforschung

Kotlarz D1, Marquardt B1, Barøy T, Lee WS, Konnikova L, Hollizeck S1, Magg T1, Lehle AS1, Walz C2, ..., Klein C1
Human TGF-ß1 deficiency causes severe inflammatory bowel disease and encephalopathy.
Nat Genet 2018; 50: 344-348 (JIF2017 27,1)
1 Kinderklinik und Kinderpoliklinik im Dr. von Hauner'schen Kinderspital
2 Pathologisches Institut

Hiddemann W1, Barbui AM, Canales MA, Cannell PK, Collins GP, Dürig J, Forstpointner R1, Herold M1, Hertzberg M, ..., Marcus RE
Immunochemotherapy With Obinutuzumab or Rituximab for Previously Untreated Follicular Lymphoma in the GALLIUM Study: Influence of Chemotherapy on Efficacy and Safety.
J Clin Oncol 2018; 36: 2395-2404 (JIF2017 26,3)
1 Medizinische Klinik und Poliklinik III

Renz BW1, Tanaka T, Sunagawa M, Takahashi R, Jiang Z, Macchini M, Dantes Z, Valenti G, White RA, ..., Wang TC
Cholinergic Signaling via Muscarinic Receptors Directly and Indirectly Suppresses Pancreatic Tumorigenesis and Cancer Stemness.
Cancer Discov 2018; 8: 1458-1473 (JIF2017 24,4)
1 Klinik für Allgemein-, Viszeral- und Transplantationschirurgie

Sibbing D1, Gross L1, Trenk D, Jacobshagen C, Geisler T, Hadamitzky M, Merkely B, Kiss RG, Komócsi A, ..., Massberg S1,
Age and outcomes following guided de-escalation of antiplatelet treatment in acute coronary syndrome patients undergoing percutaneous coronary intervention: results from the randomized TROPICAL-ACS trial.
Eur Heart J 2018; 39: 2749-2758 (JIF2017 23,4)
1 Medizinische Klinik und Poliklinik I

Stocker TJ1, Deseive S1, Leipsic J, Hadamitzky M, Chen MY, Rubinshtein R, Heckner M, Bax JJ, Fang XM, ..., Nguyen B
Reduction in radiation exposure in cardiovascular computed tomography imaging: results from the PROspective multicenter registry on radiaTion dose Estimates of cardiac CT angIOgraphy iN daily practice in 2017 (PROTECTION VI).
Eur Heart J 2018; 39: 3715-3723 (JIF2017 23,4)
1 Medizinische Klinik und Poliklinik I

Petrik D1, Myoga MH, Grade S1, Gerkau NJ, Pusch M, Rose CR, Grothe B, Götz M1
Epithelial Sodium Channel Regulates Adult Neural Stem Cell Proliferation in a Flow-Dependent Manner.
Cell Stem Cell 2018; 22: 865-878.e8 (JIF2017 23,3)
1 Physiologisches Institut, Lehrstuhl für Physiologische Genomik

Renz BW1, Takahashi R, Tanaka T, Macchini M, Hayakawa Y, Dantes Z, Maurer HC, Chen X, Jiang Z, ..., Wang TC
?2 Adrenergic-Neurotrophin Feedforward Loop Promotes Pancreatic Cancer.
Cancer Cell 2018; 33: 75-90.e7 (JIF2017 22,8)
1 Klinik für Allgemein-, Viszeral- und Transplantationschirurgie

Issels RD1, Lindner LH1, Verweij J, Wessalowski R, Reichardt P, Wust P, Ghadjar P, Hohenberger P, Angele M2, ..., Chronchi A
Effect of Neoadjuvant Chemotherapy Plus Regional Hyperthermia on Long-term Outcomes Among Patients With Localized High-Risk Soft Tissue Sarcoma: The EORTC 62961-ESHO 95 Randomized Clinical Trial.
JAMA Oncol 2018; 4: 483-492 (JIF2017 20,9)
1 Medizinische Klinik und Poliklinik III
2 Klinik für Allgemein-, Viszeral- und Transplantationschirurgie

Mahajan UM1, Langhoff E, Goni E1, Costello E, Greenhalf W, Halloran C, Ormanns S2, Kruger S3, Boeck S3, ..., Mayerle J1
Immune Cell and Stromal Signature Associated With Progression-Free Survival of Patients With Resected Pancreatic Ductal Adenocarcinoma.
Gastroenterology 2018; 155: 1625-1639.e2 (JIF2017 20,8)
1 Medizinische Klinik und Poliklinik II
2 Pathologisches Institut
3 Medizinische Klinik und Poliklinik III

Nell S, Estibariz I1, Krebes J, Bunk B, Graham DY, Overmann J, Song Y, Spröer C, Yang I, ..., Suerbaum S1
Genome and Methylome Variation in Helicobacter pylori With a cag Pathogenicity Island During Early Stages of Human Infection.
Gastroenterology 2018; 154: 612-623.e7 (JIF2017 20,8)
1 Max von Pettenkofer-Institut, Lehrstuhl für Bakteriologie

Sendler M, Weiss FU, Golchert J, Homuth G, van den Brandt C, Mahajan UM1, Partecke LI, Döring P, Gukovsky I, ..., Mayerle J1
Cathepsin B-Mediated Activation of Trypsinogen in Endocytosing Macrophages Increases Severity of Pancreatitis in Mice.
Gastroenterology 2018; 154: 704-718.e10 (JIF2017 20,8)
1 Medizinische Klinik und Poliklinik II

Öner MG1, Rokavec M1, Kaller M1, Bouznad N1, Horst D1, Kirchner T1, Hermeking H1
Combined Inactivation of TP53 and MIR34A Promotes Colorectal Cancer Development and Progression in Mice Via Increasing Levels of IL6R and PAI1.
Gastroenterology 2018; 155: 1868-1882 (JIF2017 20,8)
1 Pathologisches Institut

Winter C1, Silvestre-Roig C1, Ortega-Gomez A1, Lemnitzer P1, Poelman H, Schumski A1, Winter J1, Drechsler M1, de Jong R1, ..., Soehnlein O1
Chrono-pharmacological Targeting of the CCL2-CCR2 Axis Ameliorates Atherosclerosis.
Cell Metab 2018; 28: 175-182.e5 (JIF2017 20,6)
1 Institut für Prophylaxe und Epidemiologie der Kreislaufkrankheiten