After Forth's departure, Peter Eyer took over as acting director of the institute.
He headed the Biochemical Toxicology research group with the main aim of improving the treatment of organophosphate poisoning. To this end, the kinetic data of the individual reactions involved were determined, their interaction simulated in silico, validated in experimental models and their implementation tested in clinical studies on poisoned patients.
During the interim management phase, plans to rebuild the Walther Straub Institute in line with modern fire protection standards had been in place since the early 1990s. This mainly concerned the new building, which was only 30 years old. After many designs and drafts, the Faculty of Medicine decided to drastically reduce the size of the department and to also house forensic medicine in the building on Nußbaumstrasse. During this time, several academic positions were withdrawn from the institute or could not be refilled. As the Faculty of Medicine favored pharmacological research over toxicological research, it was finally agreed to establish a pharmacological institute in the completely renovated building of the former Physiological Chemistry Department on the corner of Pettenkoferstr. 14 and Goethestr. 33. This brought the institute into the immediate vicinity of the building in which pharmacology was established in Munich under v. Tappeiner in the former Findlingstrasse. After the renovation work in Nußbaumstrasse, a toxicology department was installed there again.
When Peter Eyer retired in 2007, Elmar Richter took over as acting director of the institute. Since May 2008, the Walther Straub Institute has once again had a full professor and is now under the direction of Prof. Dr. Thomas Gudermann.