A. W. Forst was followed in 1961 by Manfred Kiese (1910 - 1983), who was appointed to the Munich chair, which involved a new building on the site of Nussbaumstr. 28 and a conversion of the basement at Nussbaumstr. 26. In 1964 the topping-out ceremony was celebrated, and in 1969 the new institute could finally be occupied together with the new lecture hall building with 420 seats.
Manfred Kiese, born in Stettin in 1910, studied medicine at the universities of Hamburg, Frankfurt, Munich and Berlin, where he began his scientific work under Heubner and received his doctorate in 1935 for "Pharmacological Studies on the Smooth Musculature of the Lung, Particularly under the Influence of Substances with an Ephedrine-like Effect". After biochemical studies with Hastings at Harvard, he completed his habilitation with Heubner in 1939 on "Studies of the Specific Effect of Carbon Dioxide on Isolated Guinea Pig Ileum." Presumably wartime issues set the course for further research activity when Kiese investigated the acute and chronic toxicity of ingesting potassium chlorate and other substances used as explosives. Evacuated to Schleswig-Holstein, Kiese's now classic studies on the reduction of hemoglobin and on the enzymatic cycle of ferrihemoglobin formation by N-oxygenated arylamines emerged despite difficult postwar conditions. In 1950, Kiese accepted an appointment as full professor of pharmacology at the University of Marburg. Shortly before Kiese accepted an appointment to the chair in Tübingen in 1956, he worked on questions of biological N-oxygenation. After developing a sensitive method for the determination of nitrosoarenes, he succeeded, together with Uehleke, in detecting them in the blood of dogs after application of corresponding arylamines. Kiese's working group thus beat the Millers in the USA by two years. The site of biological N-oxygenation in microsomes was also soon recognized and led to intensive studies of the enzyme systems involved, which were continued in Munich by his students. Again and again, methemoglobin formation served as an indicator of N-oxygenated products. Last but not least, these studies also led to the development of a reliable antidote against hydrocyanic acid poisoning. The most valuable scientific heirloom, in addition to some 200 original papers, is undoubtedly his book "Methemoglobinemia: A Comprehensive Treatise," published in 1974.
In 1980, Wolfgang Forth accepted the call to the Munich chair from the Ruhr University in Bochum.