Kawakami Lab
Live imaging of CNS autoimmunity
Live imaging of CNS autoimmunity
© J. Greune / LMU
Live imaging of CNS autoimmunity
Institute of Clinical Neuroimmunology
+49 89 2180 71666
naoto.kawakami@med.uni-muenchen.de
Research Topics
Our research focusses on autoreactive, CNS-specific T cells that induce inflammation in the brain. The use of intravital two-photon microscopy and functional fluorescent markers in EAE, an animal model for Multiple Sclerosis, allows us to visualize not only T-cell activation but also migration and interactions with other cell types in real-time. These obtained parameters promote our understanding of how the fate of autoreactive T cells is influenced by their environment and vice versa. Read more...