Obst Lab

Lymphocyte Activation

Landscape portrait of Reinhard Obst.

© J. Greune / LMU

PD Dr. Reinhard Obst

Lymphocyte Activation
Institute of Immunology

+49 89 2180 75631
reinhard.obst@med.uni-muenchen.de

Research Topics

  • T cell activation and exhaustion
  • Interaction of T and B cells
  • Antigen processing and presentation
  • In vivo models of inducible gene expression

T cells are a key component of adaptive immunity, our natural system of defence against pathogens like bacteria and viruses. When they recognize pathogens, massive changes in their physiology occur and they differentiate into effector cells equipped with the proper means for the pathogens' removal. We investigate how these changes are regulated and explore what happens in cases the pathogen does not get cleared but persists for extended periods of time. Read more...

Scientific vita

since 2013
Lecturer, Institute for Immunology, Biomedical Center, LMU Munich
since 2006
Group leader, Institute for Immunology, Biomedical Center, LMU Munich
1998-2006
Postdoctoral researcher, IGBMC Strasbourg, France, and Harvard Medical School, Boston, USA (C. Benoist and D. Mathis Labs)
1998
PhD in Biology, University of Konstanz, Advisors: U. Krawinkel and H.-G. Rammensee, Tübingen