Heissmeyer Lab
Post-transcriptional gene regulation in T cells
© C. Olesinski / LMU
Prof. Dr. Vigo Heissmeyer
Post-transcriptional gene regulation in T cells
Institute of Immunology
+49 89 2180 75629
vigo.heissmeyer@med.uni-muenchen.de
Research Topics
- Post-transcriptional control of T cell differentiation
- Function of RNA-binding proteins and m6A RNA methylation
- Global analysis of binding Sites in the transcriptome
- Autoimmunity and anti-tumor immmunity
T lymphocytes require well-adjusted transcriptional and post-transcriptional gene expression programs to initiate immune responses against pathogens. Surprisingly, even in the absence of infections they similarly depend on active post-transcriptional gene regulation to remain silent and not cause damage to the body’s own tissues. Our work aims to decipher how RNA-binding proteins control T cell quiescence and shape activation, differentiation and effector functions. Read more...
Publications
Scientific vita
- since 2012
- Professor, Institute for Immunology, Biomedical Center, LMU Munich
- since 2005
- Group leader, Research Unit Molecular Immune Regulation, Helmholtz Munich
- 2001-2005
- Postdoctoral researcher, Rao Lab, Harvard Medical School, Boston, USA
- 2000
- Postdoctoral researcher, Scheidereit Lab, Max Delbrück Center Berlin
- 1999
- PhD in Biology, Freie Universität Berlin, Advisor: Claus Scheidereit