PhD Position – Circadian Desynchronization and Epigenetic Crosstalk in Metabolic Steatohepatitis (Project B02)
Location
Ludwig Maximillians University Munich
Institute
Institute of Medical Psychology and Biomedical Center (BMC)
Start date
October 1, 2025
Application deadline
August 8, 2025
Employment
65%, TV-L – E13, fixed-term until June 30, 2029
Contact
Prof. Dr. Maria Robles
crobles@med.lmu.de
Description
We are seeking a motivated PhD student with a Master's degree in biochemistry, bioinformatics, or a related field to investigate circadian proteomic signatures in metabolic dysfunction-associated steatohepatitis (MASH). The project involves working with in vitro, ex vivo, and in vivo mouse models as well as human blood and liver biopsy samples. The work is embedded in a collaborative environment within the CRC on Circadian Medicine.
RESPONSIBILITIES
- Conduct circadian proteome analysis using samples from mouse models and human tissues
- Use Integratated computational approaches to analyize proteomic and transcriptomic data to identify molecular rhythms
- Prepare biological samples for quantitative proteomics mass spectrometry and perform mass spectrometry measurements and data processing.
- Collaborate within the project team and contribute to CRC-wide research efforts
REQUIREMENTS
- Master's degree in biochemistry, bioinformatics, or a related field
- Experience in computational analysis and integration of large-scale omics datasets
- Ideally, hands-on experience in mass spectrometry-based proteomics, including samplepreparation and data analysis
- High motivation to work independently and collaboratively in a dynamic and interdisciplinary research environment