AG Stark

Dr. med. Konstantin Stark
Affiliation: University Hospital LMU Munich, Department of Medicine I – Cardiology

Research Focus:
Dr. Stark investigates the cellular and molecular mechanisms underlying thromboinflammation, with a focus on how platelets, immune cells, and the endothelium interact to drive cardiovascular disease. His research aims to identify novel targets for anti-thrombotic and anti-inflammatory therapies by dissecting these interactions in dynamic, disease-relevant contexts.

Role in ICON:
Within ICON’s research on vascular disease and inflammatory mechanisms, Dr. Stark leads studies on platelet–leukocyte signaling, immune-mediated thrombosis, and vascular inflammation. He works across both experimental and translational domains, using preclinical models and patient-derived data to uncover mechanisms and therapeutic strategies.

Key Areas of Work:

  • Platelet–neutrophil and platelet–endothelium interaction
  • Thrombus formation and resolution in vascular disease
  • Inflammatory mechanisms in atherosclerosis and thrombosis
  • Translational biomarker development

Techniques & Infrastructure:

  • Flow cytometry and immune cell phenotyping
  • Intravital microscopy in vascular beds
  • Mouse and porcine models of vascular inflammation
  • Cross-analysis with human cardiovascular samples