PD Dr. med. Leo Nicolai
Affiliation: University Hospital LMU Munich, Department of Medicine I – Cardiology
Research Focus:
Dr. Nicolai's research focuses on immunothrombosis and the interplay between neutrophils, platelets, and the coagulation cascade in cardiovascular diseases. His work has provided insights into the mechanisms of thromboinflammation and potential therapeutic targets.
Role in ICON:
Dr. Nicolai contributes by leading studies on neutrophil-driven thrombosis and vascular inflammation, utilizing both mechanistic studies and translational applications of immune-modulating therapies.
Key Areas of Work:
- Neutrophil–platelet interactions in thrombosis
- Immunothrombosis in cardiovascular diseases
- Therapeutic modulation of innate immune activation
Techniques & Infrastructure:
- Flow cytometry and immune cell profiling
- Intravital microscopy of thrombus formation
- Animal models of atherosclerosis and thromboembolism