AG Michel

PD Dr. med. Sebastian G. Michel
Affiliation: LMU University Hospital, Department of Cardiac Surgery

Research Focus:
Dr. Michel focuses on xenotransplantation, mechanical circulatory support, and advanced heart failure surgery. His group investigates how genetically modified organs, novel immunomodulatory protocols, and device-based therapies can be translated from preclinical models to clinical application.

Role in ICON:
Dr. Michel contributes to research on myocardial, rhythm, and valve disorders, leading experimental surgical programs that test innovative therapies in porcine models. His group also supports cross-thematic efforts in transplantation and circulatory support.

Key Areas of Work:

  • Heart xenotransplantation models
  • Surgical strategies for end-stage heart failure
  • Device testing and post-op tissue analysis

Techniques & Infrastructure:

  • Pig heart transplantation procedures
  • Hemodynamic monitoring and tissue sampling
  • Integration with biobanking and histopathology