Prof. Dr. med. Florian Gärtner
Affiliation: University Hospital LMU Munich, Department of Medicine I – Cardiology
Research Focus:
Prof. Gärtner's research centers on the mechanobiology of cell migration, particularly how mechanical forces influence the behavior of cells within the cardiovascular system. His work aims to elucidate the mechanical processes that govern cell shape and movement in living tissues, with significant implications for cardiovascular biology.
Role in ICON:
Within ICON Prof. Gärtner contributes to understanding the mechanical aspects of cell migration and their impact on cardiovascular diseases. His expertise supports investigations into how mechanosensing and mechanotransduction affect vascular remodeling and disease progression.
Key Areas of Work:
- Mechanosensing and Mechanotransduction: Studying how cells detect and respond to mechanical stimuli in the cardiovascular context.
- Platelet Formation and Function: Investigating the role of mechanical forces in platelet biogenesis and their implications for thrombosis.
- Cell Migration in 3D Tissues: Exploring the dynamics of cell movement within three-dimensional tissue environments to better understand processes like angiogenesis and tissue repair.
Techniques & Infrastructure:
- Advanced Microscopy: Utilizing high-resolution imaging techniques to observe cell behavior in real-time.
- 3D Tissue Models: Developing and employing three-dimensional models to study cell migration and interaction within a tissue-like context.
- Biophysical Tools: Applying tools to measure and manipulate mechanical forces at the cellular level to dissect mechanotransduction pathways.