AG Brendel

Prof. Dr. med. Matthias Brendel
Affiliation: LMU University Hospital, Department of Nuclear Medicine

Research Focus:
Prof. Brendel's work focuses on molecular imaging of inflammation, neurodegeneration, and tissue remodeling, particularly using PET tracers in preclinical and translational settings. His expertise includes validating radiotracers and linking image-derived data with cellular and molecular pathology.

Role in ICON:
Prof. Brendel supports ICON’s focus on vascular and metabolic disorders by developing imaging strategies to assess inflammatory pathways, fibrotic remodeling, and cellular activation in large-animal disease models.

Key Areas of Work:

  • Immunometabolic PET imaging
  • Molecular tracer validation
  • Correlation of imaging biomarkers with histopathology

Techniques & Infrastructure:

  • PET/MR and multimodal preclinical imaging
  • Radiotracer development and kinetic modeling
  • Translational protocols aligned with human applications