Prof. Dr. rer. nat. HDR Anne-Laure Boulesteix

Institut für Medizinische Informationsverarbeitung, Biometrie und Epidemiologie

Professur für Biometrie mit Schwerpunkt molekulare Medizin

Büroadresse:

Marchioninistr. 15

81377 München

Brief CV

Anne-Laure Boulesteix obtained a diploma in engineering from the Ecole Centrale Paris, a diploma in mathematics from the University of Stuttgart (2001) and a PhD in statistics (2005) from the Ludwig Maximilian University (LMU) of Munich. After a postdoc phase in medical statistics, she joined the Medical School of the University of Munich as a junior professor (2009) and professor (2012). She is working at the interface between biostatistics, machine learning and medicine with a particular focus on metascience and evaluation of methods. She is a PI in the Munich Center for Machine Learning, steering committee member of the STRATOS initiative, founding member of the LMU Open Science Center and former president and vice-president of the German Region of the International Biometric Society (2022-2026).

  • Since May 2012: Associate professor (W2, tenured) at the Department of Medical Informatics, Biometry and Epidemiology of the Faculty of Medicine, LMU Munich (Germany)

  • 2009-2012: Assistant professor (W1) at the Department of Medical Informatics, Biometry and Epidemiology of the Faculty of Medicine, LMU Munich (Germany)

  • 2008: Visiting professor of biostatistics at the Department of Statistics, LMU Munich (Germany)

  • 2007-2008: Statistician at the Sylvia Lawry Centre for Multiple Sclerosis Research e.V. in Munich (Germany)

  • 2005-2007: Post-doc at the University Hospital „Klinikum Rechts der Isar“ of the Technical University of Munich (Germany)

  • 2002 – 2006: Researcher at the Department of Statistics, LMU Munich (Germany)

  • 2011: French "Habilitation à diriger les recherches", University of Evry Val d'Essonne (near Paris, France)

  • 2005: PhD in Statistics at LMU Munich (Germany)

  • 2001: Diploma in Mathematics at the University of Stuttgart (Germany)

  • 2001: M.Sc. in Engineering (diplôme d'ingénieur) at the Ecole Centrale Paris (France)

  • 1979: Born in Paris (France)

Research Interests

Metascience (research on research methodology) focused on statistical and health sciences:

  • validation and validity of research results
  • (design of) neutral comparison studies in methodological research
  • design and analysis of benchmarking experiments
  • statistical simulation studies
  • publication bias, selective reporting, optimistic bias
  • reporting of scientific results

Medical/computational statistics:

  • analysis of high-dimensional omics data
  • model selection for multivariable regression, regularized regression
  • resampling techniques, error estimation
  • added predictive value, relative importance of predictors
  • machine learning (e.g., random forest)

Statistical consulting in medical research

Editorial activities:

Main Teaching Activities

  • Preclinical and Clinical Studies (2021-2023), lecture for statistics/biostatistics students (master). LMU Munich.
  • Open Replicable Science (2021-2023), lecture for statistics/biostatistics students (master). LMU Munich.
  • Bachelor seminar on topics related to biostatistics and replicable science (2013-2023). LMU Munich.
  • Diagnostic Accuracy Studies (2022), lecture for statistics/biostatistics students (master). LMU Munich.
  • Statistical Pitfalls in Medical Research (2022), lecture for statistics/biostatistics students (master). LMU Munich.
  • Multiple Testing (Part of Clinical Epidemiology II) (2015-2023), lecture and tutorials for epidemiology students (master). LMU Munich.
  • Advanced Biometry (2018-2023), flipped classroom for epidemiology students (master). LMU Munich.
  • Various statistics courses for MD students (since 2009).
  • Introduction to Medical Biometry (2016-2021), lecture and tutorials for statistics students (bachelor). LMU Munich.
  • Medical Statistics (2010-2021), seminar for statistics students (bachelor and master) with focus either on observational studies, randomized controlled trials, good statistical practice/reproducibility, etc. LMU Munich.
  • Biostatistical Methods (2015-2020), lecture for statistics/biostatistics students (master). LMU Munich.
  • Applied Statistics in Epidemiology (2016-2021), joint seminar for statistics and epidemiology students (master). LMU Munich.
  • Longitudinal Data Analysis (2008-2014), lecture for statistics/biostatistics students (master). LMU Munich.
  • Medical Statistics (2008), lecture for mathematics students (master) at the Ecole Centrale Paris (France).
  • Biostatistics (2007), lecture for mathematics students (master) at the Ecole Centrale Paris (France)
  • Medical Statistics (2005-2006), computer courses for medical students. TU Munich.
  • Nonparametric Statistics (2005-2006), tutorials for statistics students (master). LMU Munich.
  • S-Plus (2004-2005), computer course for statistics students (bachelor). LMU Munich.
  • Multivariate Statistics (2002-2003), tutorials for statistics students (master). LMU Munich.
  • Statistics I, II and IV, tutorials for economics students (2002-2004). LMU Munich.

Publikationsliste