Mayerhofer Lab

We are interested in fundamental questions of human reproduction in health and disease (infertility). Our models include human testicular and ovarian cells. We use various cellular and molecular techniques and cooperate with groups at the BMC, the Gene Center and with national and international partners.

Head

Landscape portrait of Artur Mayerhofer.

© J. Greune / LMU

Prof. Dr. Artur Mayerhofer

+49 89 2180 75859
mayerhofer@bmc.med.lmu.de

Research Topics

  • Function and regulation of testicular peritubular cells
  • Function and regulation of ovarian granulosa cells
  • Granulosa cell tumors

Scientific vita
since 2000
Professor of Molecular Anatomy, Dept. Cell Biology, Biomedical Center, LMU Munich
since 1996
Professor of Molecular Anatomy, Anatomy, TU Munich
1993-1996
Heisenberg Fellow (DFG), OHSU, ONPRC, Portland/Beaverton, Oregon, USA
1992-1993
Research Associate, Schering AG, Berlin
1992
Habilitation (Anatomy), University of Ulm
1987-1992
Postdoctoral Researcher, Anatomy and Cell Biology, University of Ulm and Department of Physiology, SIU Carbondale, Illinois, USA

Publications

https://orcid.org/0000-0002-9388-4639

Top5 Publications

Mayerhofer A, Dissen GA, Costa ME, Ojeda SR. A role for neurotransmitters in early follicular development: induction of functional follicle-stimulating hormone receptors in newly formed follicles of the rat ovary. Endocrinology. 1997 Aug;138(8):3320-9.

Mayerhofer A, Smith GD, Danilchik M, Levine JE, Wolf DP, Dissen GA, Ojeda SR. Oocytes are a source of catecholamines in the primate ovary: evidence for a cell-cell regulatory loop. Proc Natl Acad Sci U S A. 1998 Sep 1;95(18):10990-5.

Pfeifer A, Klatt P, Massberg S, Ny L, Sausbier M, Hirneiss C, Wang GX, Korth M, Aszódi A, Andersson KE, Krombach F, Mayerhofer A, Ruth P, Fässler R, Hofmann F. Defective smooth muscle regulation in cGMP kinase I-deficient mice. EMBO J. 1998 Jun 1;17(11):3045-51.

Frungieri MB, Weidinger S, Meineke V, Köhn FM, Mayerhofer A. Proliferative action of mast-cell tryptase is mediated by PAR2, COX2, prostaglandins, and PPARgamma: Possible relevance to human fibrotic disorders. Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):15072-7.

Nie X, Munyoki SK, Sukhwani M, Schmid N, Missel A, Emery BR, DonorConnect, Stukenborg JB, Mayerhofer A, Orwig KE, Aston KI, Hotaling JM, Cairns BR, Guo J. Single-cell analysis of human testis aging and correlation with elevated body mass index. Dev Cell. 2022 May 9;57(9):1160-1176.e5.

Research Topics

Our research focuses on the human gonads. We use mainly cellular models to better understand the

1. Function and regulation of testicular peritubular cells

2. Function and regulation of ovarian granulosa cells and ovarian granulosa cell tumors

Team

NameTitleEmailTelephonePosition
Eubler, KatjaDr.katja.eubler@bmc.med.lmu.de+49 89 2180 75866Postdoc
Herrmann, Carolacarola.herrmann@bmc.med.lmu.de+49 89 2180 75866Technician
Jiang, YuhaoYuhao.Jiang@bmc.med.lmu.de+49 89 2180 75866Doctoral researcher
Liebich, AnnikaDr.annika.liebich@bmc.med.lmu.de+49 89 2180 75861Postdoc
Schneider, Michaelamichaela.schneider@bmc.med.lmu.de+49 89 2180 75861Doctoral researcher
Scholz, Linalina.scholz@bmc.med.lmu.de+49 89 2180 75861Doctoral researcher
Welter, HaraldDr.welter@bmc.med.lmu.de+49 89 2180 75836Postdoc

Gallery (optional)

  1. Pipetting with a multi-channel pipet.
  2. Several sealed samples side by side
© J. Greune / LMU
© LMU