van Bömmel Lab
Neuroepigenetics and Data Science
Neuroepigenetics and Data Science
© D. Ausserhofer
Neuroepigenetics and Data Science
Division of Metabolic Biochemistry
alena.vanboemmel@mail03.med.uni-muenchen.de
Research Topics
Our lab works at the intersection of epigenetics and computational biology, with a goal to unravel the complex roles of epigenetic changes in human aging and cancer. Our research focuses on the development and application of machine learning models on high-dimensional multi-omics data sets such as DNA methylation, histone modification and open chromatin. On one hand, we work on the development of interpretable epigenetic clocks and statistical models of epigenetic dynamics during aging. We also investigate the unique epigenetic signatures associated with various cancers, such as brain tumors or leukemias to detect powerful diagnostic markers or predictors of therapeutic response.