Liebscher Lab
Circuit mechanisms of neurodegenerative disorders
Dr. Sabine Liebscher
Circuit mechanisms of neurodegenerative disorders
Institute of Clinical Neuroimmunology
+49 89 2180 71659
sabine.liebscher@med.uni-muenchen.de
Research Topics
- Cellular and circuit mechanisms of Amyotrophic Lateral Sclerosis
- Circuit dysfunction in anti-NMDAR autoimmune encephalitis
- Astrocyte physiology and pathophysiology in vivo
- Sensorimotor integration using two-photon imaging in behaving mice
Our main aim is to unravel the cellular and circuit mechanisms that contribute to CNS disorders in order to identify therapeutically amenable circuit elements as novel strategies to combat these disorders. To this end we employ cutting-edge in vivo imaging to chronically study the structure and function of neurons and glia cells at single cell/synapse resolution in behaving mice. These in vivo studies are complemented by a variety of additional methods, such as circuit mapping, chemogenetic manipulation, region- and cell type-specific transcriptomic and proteomic analyses etc. Read more...
Publications
Scientific vita
- since 2025
- Director of the Institute of Neurobiochemistry, Medical University Innsbruck, Austria
- 2023-2024
- W2 Professor for Cellular Neurophysiology, University of Cologne & University Hospital Cologne, Dept. of Neurology, Germany
- 2017-2024
- Emmy Noether Group leader, Institute of Clinical Neuroimmunology, University Hospital and Biomedical Center, LMU Munich
- 2014
- Clinician scientist group leader, Resident in Neurology, Institute of Clinical Neuroimmunology, University Hospital and Biomedical Center, LMU Munich
- 2008-2014
- PhD studies, Max Planck Institute of Neurobiology, Martinsried, and Dept. Biochemistry, LMU Munich
- 2007-2008
- Research assistant, Rockefeller University, New York City, USA
- 2007
- MD, Technical University of Dresden