Götz Lab

Neurogenesis

Landscape portrait of Magdalena Götz.

© J. Greune / LMU

Prof. Dr. Magdalena Götz

Neurogenesis
Division of Physiological Genomics

+49 89 2180 75255
magdalena.goetz@helmholtz-muenchen.de

Research Topics

  • Neural stem cells
  • Neurogenesis
  • Glia-to-neuron reprogramming
  • Neuronal repair

We study the mechanisms of brain development and neurogenesis to understand basic novel mechanisms of neural stem cell self-renewal and differentiation and mechanisms of neuronal fate specification which we can then transfer aiming towards repair. Neurons are not replaced after injury or in neurodegenerative disease. We have therefore pioneered the approach to turn local glial cells in the adult mammalian brain into new neurons and now work on improving this conversion, examining the integration of the new neurons and targeting scar-forming glia for reprogramming to also alleviate scar-formation. Read more...

Scientific vita

since 2011
W3 Professorship in the Dept. of Physiological Genomics, Biomedical Center, LMU Munichsince
2004
Chair of Physiological Genomics, Medical Faculty, LMU Munichsince
2004
Director of the Stem Cell Institute, GSF – since 01.01.2008: Helmholtz Zentrum München, Neuherberg-Munich
1997-2003
Group Leader at the Max-Planck Institute of Neurobiology, Martinsried
1997
Scientist, Max-Planck Institute of Biophysical Chemistry, Göttingen
1994-1996
Postdoctoral Scientist, SmithKline Beecham Harlow, U.K
1993-1994
Postdoctoral Fellow, National Institute for Medical Research, London, U.K.
1992
PhD in Biology, Friedrich-Miescher Institute of the Max-Planck Society, Tübingen