Becker Lab
Chomatin Dynamics
© J. Greune / LMU
Prof. Dr. Peter Becker
Chromatin Dynamics
Division of Molecular Biology
+49 89 - 2180 75427
pbecker@bmc.med.lmu.de
Research Topics
- Chromosome-wide gene regulation
- Long, non-coding roX RNA
- Variant histone dynamics
- Factor cooperativity in chromosomal locus control
We explore the principles and mechanisms of regulation of genome functions through chromatin organisation. We are particularly interested in ATP-dependent nucleosome ‘remodeling’ machines and in the mechanisms of transcriptional fine-tuning during dosage compensation. Our model organism is Drosophila melanogaster. We employ a wide range of methods from biochemistry, genomics, cell biology, reverse genetics and collaborate with colleagues on structural aspects. Our methodological specialty is the reconstitution of chromatin structure and function on a genome-wide scale in cell-free systems (genome-wide biochemistry). Read more...
Publications
Scientific vita
- since 1999
- Professor of Molecular Biology at the Dept. of Molecular Biology, Biomedical Center, LMU Munich
- 1991-1999
- Group leader at European Molecular Biology Laboratory, Heidelberg
- 1988-1991
- Postdoctoral researcher in Carl Wu's Lab, NIH, National Cancer Institute, USA
- 1987
- PhD in Biology at the University of Heidelberg, Advisor: Günther Schütz