Schotta Lab
Epigenetic Gene Regulation
© J. Greune / LMU
Prof. Dr. Gunnar Schotta
Epigenetic Gene Regulation
Division of Molecular Biology
+49 89 2180 75422
gunnar.schotta@bmc.med.lmu.de
Research Topics
- Control of endogenous retroviruses
- Heterochromatin silencing mechanisms
- Transcription factor biology
- Epigenetic alterations in cancer
Epigenetic mechanisms regulate multiple aspects of normal development (stem cell maintenance, differentiation). Misregulation of epigenetic programs can result in aberrant development (cancer, aging). In this context we study the mechanisms of epigenetic gene regulation using a combination of mouse genetics (knock-out and knock-in mouse models), cell biology (embryonic stem cells, differentiation systems, CRISPR/Cas, genome-wide sgRNA screens) and biochemical (ChIP-seq, RNA-seq, MeDIP-seq, ATAC-seq, etc.) approaches. Read more...
Publications
Scientific vita
- since 2008
- Professor for Epigenetics, Dept. Molecular Biology, Biomedical Center, LMU Munich
- 2003-2008
- Postdoctoral researcher, Thomas Jenuwein Lab, Institute of Molecular Pathology (I.M.P.), Vienna, Austria
- 2002-2003
- Postdoctoral researcher, Gunter Reuter Lab, Martin Luther University Halle
- 2002
- PhD in Molecular Genetics, Martin Luther University Halle, Advisor: Gunter Reuter