Masserdotti Lab

Vergrößern

Dr. Giacomo Masserdotti

Cell fate and metabolism
Division of Physiological Genomics

+49 89 2180 71093
Giacomo.masserdotti@bmc.med.lmu.de

Research Topics

• Direct neuronal reprogramming
• Metabolism
• Cell identity
• Organelle heterogeneity

We investigate the mechanisms driving the direct reprogramming of differentiated mouse and human cells into functional neurons, aiming at a comprehensive understanding of the conversion process with the final aim of further improvement of purity and quality of the induced neurons. Leveraging state-of-the-art technologies — including single-cell multiomics, proteomics, metabolomics and high-content imaging — we aim to understand the extent to which the identity of differentiated cells can be manipulated to generate new neurons that are functionally and molecularly similar to those present in the adult healthy brain. Read more...

Publications

https://orcid.org/0000-0003-3621-3481

Scientific vita