Deindl Lab
Arteriogenesis
Arteriogenesis
© J. Greune / LMU
Arteriogenesis
Institute of Cardiovascular Physiology and Pathophysiology
+49 89 2180 76504
elisabeth.deindl@med.uni-muenchen.de
Research Topics
We investigate the molecular mechanisms of arteriogenesis, i.e. the growth of pre-existing arteriolar connections into functional bypasses. For our studies, we employ a murine hindlimb model. In detail, we are studying how increased shear stress, the trigger of arteriogenesis, is translated into biological signals, and how these signals are propagated within a cell as well as from cell to cell. Moreover, we are investigating the functional role of the innate immune system. Besides a variety of molecular and immunohistological analyses, we perform in vitro studies. Read more...